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# Welcome to CD38 Central
Keywords: CD38, immune-mediated diseases, antibody-mediated rejection, kidney transplantation, IgA nephropathy, primary membranous nephropathy, felzartamab, immune cells, therapeutic target

> CD38 Central is an educational hub dedicated to exploring the science of CD38⁺ immune cells and their role in immune-mediated diseases, offering resources, research insights, and emerging therapeutic approaches.

## Details
- [Explore the Science](#): Discover featured materials on CD38⁺ immune cells and their impact on immune-mediated diseases.
- [Antibody-Mediated Rejection in Kidney Transplantation](#): Learn about the role of CD38⁺ plasma cells and NK cells in donor-specific antibody generation and graft injury mechanisms.
- [The Role of CD38⁺ Cells in Immune-Mediated Diseases](#): Understand how CD38⁺ cells contribute to inflammation and tissue damage across various kidney diseases.
- [Prolonged CD38 Targeting with Felzartamab](#): Explore a Phase 2 study on the effects of felzartamab in managing antibody-mediated kidney transplant rejection.
- [Antibody-Mediated Rejection & Microvascular Inflammation](#): Insights into how CD38⁺ plasma cells and NK cells mediate allograft injury in kidney transplantation.
- [IgA Nephropathy](#): Examine the role of CD38⁺ plasmablasts and plasma cells in the pathogenesis of IgA nephropathy.
- [Primary Membranous Nephropathy](#): Study the involvement of CD38⁺ cells in producing pathogenic autoantibodies in primary membranous nephropathy.
- [Immune-Mediated Diseases](#): Access educational resources on disease mechanisms, unmet needs, and scientific advancements.
- [Manuscripts](#): Review research on CD38⁺ cells, disease biology, and the investigational monoclonal antibody felzartamab.
- [Pipeline](#): Explore ongoing research on felzartamab, including its scientific rationale and clinical investigations.
- [Frequently Asked Questions](#): Find answers about CD38, its function, felzartamab, and its targeted diseases.

Master Metadata [TARGET AUDIENCE - HCPs] RESOURCE SET

Master Metadata [CONTENT TYPE - MEDICAL EDUCATION] RESOURCE SET

Master metadata [FORMAT - TEXT, PDF, INTERACTIVE CONTENT, IMAGE, VIDEO]

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Master Metadata [MARKET - United States] RESOURCE SET

Master Metadata [PRODUCT - Felzartamab] RESOURCE SET

Master Metadata [PROMO - NON - PROMO] RESOURCE SET

Master Metadata [REGION - United States] RESOURCE SET

Master Metadata [SCIENTIFIC CONTENT - YES] RESOURCE SET

Master Metadata [TA - General Antibody Mediated Rejection, General IgA Nephropathy, General Nephrology, General Primary Membranous Nephropathy] RESOURCE SET

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CD38 Central logo with the text "A hub for the science of CD38 and immune-mediated diseases" next to 3D illustrations of immune cells and antibodies.

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<p style="color:#FCD436"; size="1.5"><b>EXPLORE THE SCIENCE</b></p>
<h3>Featured materials</h3>

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### Explore the Role of CD38<sup>+</sup> Cells in Immune-Mediated Diseases

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<p style="color:#216EB7"; size="1.5"><b>FREQUENTLY ASKED QUESTIONS</b></p>
<h3>Frequently asked questions about CD38, felzartamab, and immune-mediated diseases</h3>

*Felzartamab is an investigational monoclonal antibody whose safety and efficacy have not been established and has not been approved for use by any regulatory authority.*

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A hub for the science of CD38 and immune-mediated diseases

CD38 Central